Future Pulse Cardiology
Investigating Innovative Cardiovascular Research at the Intersection of Academic Theory and Clinical Practice. In these discussions we take a deep dive into the latest research and how it informs current practice. For a patient level discussion, please listen to PATIENT PULSE. Available on Apple Podcasts, Spotify, YouTube and most other services. Subscribe to have new podcasts sent directly to your player and please email us with any comments. We would love to hear from you.
Episodes
22 episodes
Inflammation and Cardio-Rheumatology with Dr Nehal Mehta
Dr Thomas Nero discusses inflammation and the role of rheumatologic disorders on coronary artery disease with Dr Nehal Mehta, exploring how chronic inflammation serves as a cornerstone for various health issues, particularly in patients with co...
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Season 3
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Episode 6
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52:03
Coronary Inflammation Imaging with FAI Score on CT angiography with Prof. Stefan Neubauer
Prof. Stefan Neubauer and Dr. Thomas Nero discuss two recent papers on the utility of coronary inflammation imaging on CT coronary angiography with Fat Attenuation Index (FAI)FAI score. The ORFAN study demonstrated a 20 fold increa...
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Season 3
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Episode 5
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45:30
Trial Statistics, Trial Design and AI with Dr. C Michael Gibson
Dr Gibson and Dr Nero discuss the oft maligned issue of medical statistics. Their discussion covers the pros and cons of traditional Cox proportional hazards regression models and Kaplan-Meier curves and newer techniques including win rat...
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Season 3
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Episode 4
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34:28
Deep Dive into Lp(a) with Dr Steven Nissen Part 2 of 2
This episode is a deep dive into Lipoprotein a with Dr Steven Nissen from the Cleveland Clinic. He and Dr Nero discuss the genetics of Lp(a), its pathophysiology, current treatment strategies and research into lowering Lp(a) levels. ...
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Season 3
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Episode 3
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48:10
Lp(a): a basic clinical approach with Dr. Steven Nissen Part 1 of 2
Dr Steven Nissen from the Cleveland Clinic discuses with Dr. Thomas Nero the basic clinical approach to Lp(a) with need for routine testing and a few simple case studies. In the second (longer podcast) they take a deep deep dive into Lp(a...
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Season 3
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Episode 2
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11:00
Coronary Artery Disease in the Endurance Athlete with Dr Aaron Baggish
Dr Thomas Nero speaks with Dr Aaron Baggish about coronary artery disease in the endurance athlete (and non-athlete as well!) They discuss cardiovascular testing in Masters athletes including ETT, coronary calcium scoring and CT angiograp...
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Season 3
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Episode 1
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41:40
Atrial Fibrillation and Clinical Trials with Dr John Mandrola
Dr Mandrola discusses recent trail data with Dr. Thomas Nero including the results from Artesia, NOAH Afnet 6, Frail AF, Azalea and Oceanic-AF. They also discuss Left Atrial Appendage Occlusion and utility of wearable devices. Final...
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Season 2
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Episode 7
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48:30
Coronary Calcium Score and CT Coronary Angiography with Dr. Mathew Budoff
Dr. Thomas Nero speaks with Dr. Mathew Budoff about Coronary Calcium Scoring, CT Coronary Angiography and cardiovascular outcomes. The discussion goes beyond basic risk factor enhancement, highlighting its role to help evaluate disease pr...
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Season 2
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Episode 6
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24:35
Dr Elizabeth Ofili and The African American Heart Study
Dr. Elizabeth Ofili discusses the African American Heart Study with Dr. Thomas Nero. They also discuss her work at the NIH and the African American Heart Failure Trial and the role of community based pragmatic clinical trials.
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Season 2
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Episode 5
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34:24
Anticoagulation, Thombin Generation and Factor XI inhibition in ACS and Atrial Fibrillation with Dr C. Michael Gibson
Dr. Thomas Nero discusses current therapy with Factor X inhibitors, the new research with Factor XI inhibition and specifically the enrolling Milvexian clinical trials with Dr. C Micahel Gibson. In addition they discuss, the addition of t...
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Season 2
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Episode 4
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30:16
Diabetes and Cardiovascular Disease, SGLT2 inhibitors and GLP1 receptor agonists with Dr. Peter Toth
Dr. Thomas Nero speaks with Dr Peter Toth about the dramatic change occuring in diabtetes management and its effect on cardiovascular disease. Starting with the biochemestry of diabetes and its effects at the cellular level, the discussio...
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Season 2
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Episode 3
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45:58
Lipids, Lipid Sub-fractionations and Inflammation, Putting It All Together with Dr Peter Toth
Dr. Thomas Nero speaks with Dr. Peter Toth about the complex biology of lipids and atherosclerosis. In this episode Dr Toth dives into LDL goals, therapies for attenuating non-LDL risk, vascular biology and the where are research studies ...
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Season 2
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Episode 2
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34:58
Inflammation and Coronary Artery Disease with Dr Paul Ridker
Dr Paul Ridker discusses his paper on residual inflammatory risk that was recently published in the Lancet with Dr. Thomas Nero. He discusses the pathology of inflammation as part of atherosclerosis, utilization of hs-CRP in clinical tria...
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Season 2
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Episode 1
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40:52
Pragmatic Clinical Trials and EVOLVE-MI with Dr Christopher Cannon
Dr Christopher Cannon discusses the potential of Pragmatic Clinical Trials in our research armamentarium with Dr. Thomas Nero. They review the EVOLVE-MI trial for Early use of Evolocumab after Myocardial Infarction in detail and highligh...
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Episode 8
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21:01
Spontaneous Coronary Artery Dissection (SCAD) with Dr. Sharonne Hayes Part 2
Dr Sharoanne Hayes and Dr. Thomas Nero continue their discussion of SCAD focusing on genetics, trial design and the role of online registries as well as the holistic treatment of the SCAD patient. This is part two of two.
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Episode 7
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23:42
Spontaneous Coronary Artery Dissection (SCAD) with Dr. Sharonne Hayes Part 1
Dr Sharonne Hayes of the May Clinic discusses SCAD with Dr. Thomas Nero. Initially focusing on the new treatment paradigms, their wide ranging discussion covers etiology, pathophysiology and potential future therapeutic options. Tis...
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Episode 6
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26:13
Evaluation of Coronary Inflammation with CT angiography and Fat Attenuation Indexing
Dr. Nero discusses evaluation of coronary artery disease and coronary inflammaiton with Dr. Cheerag Shirodaria from the University of Oxford. Dr. Shirodaria along with Prof. Charalambos Antonidies at Caristo Diagnostics have develop...
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Episode 5
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28:00
Legal Aspects of FDA approval and implications for clinical research
Prof. Christine Coughlin of Wake Forest School of Law speaks with Dr. Thomas Nero on the FDA approval process, emergency use authorization, Right to Try Legislation and the implications for clinical research, diversity and health care equity.&n...
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Episode 4
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23:13
Coronary Artery Disease in the Athlete with Dr Paul Thompson
Although exercise usually provides a cardiovascular benefit, there is some data that points to an increase in event rates in extreme endurance athletes. In this episode, Dr. Thomas Nero and Dr. Paul Thompson discuss the surprising finding...
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Episode 3
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23:31
Statin Associated Muscle Symptoms with Dr Thomas Nero and Dr Paul Thompson
Dr Nero and Dr Thomposn discuss Statin Associated Muscle Symptoms (SAMS) and the results of the STOMP and SAMSON trials. In addition, they discuss statins and athletic training, options for the statin intolerant patient and research regar...
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Episode 2
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22:41
CAD, Lipid Sub-fractionation and Lp(a) with Dr Paul Thompson
Our inaugural podcast is a discussion between Dr. Paul Thompson, Chief of Cardiology, Emeritus, at Hartford Hospital and Professor of Medicine, Emeritus, at University of Connecticut and Dr. Thomas Nero, Director of Cardiovascular Research at C...
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Episode 1
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20:43
